Cannflavines: de verborgen kracht van de cannabisplant

Cannflavins: The Hidden Power of the Cannabis Plant

Cannflavins: The Hidden Power of the Cannabis Plant

When you think of the cannabis plant, CBD and THC often come to mind first. Yet, there's much more to this versatile plant. One of the most intriguing discoveries of recent years is cannflavins —a rare group of flavonoids found exclusively in cannabis and arousing the curiosity of scientists worldwide.


What makes cannflavins so special?

Flavonoids are plant compounds known for their antioxidant and protective effects. Consider the health benefits of fruits and vegetables: flavonoids play a role there as well. But cannflavins are different. Thanks to their unique chemical structure—enriched with prenyl or geranyl groups—they possess properties found in no other plant.

So far, four major cannflavins have been identified:

  • Cannflavin A – the most researched and most potent.

  • Cannflavin B – closely related, but with subtle chemical differences.

  • Cannflavin C – rarer, but biologically active.

  • Isocannflavin B – a variant with unique therapeutic potential.


Promising effects according to research

A growing number of scientific studies point to the impressive health benefits of cannflavins. Some highlights:

  • Anti-inflammatory – Cannflavin A and B have been shown to be up to thirty times more potent than aspirin, without the known side effects of NSAIDs.

  • Neuroprotective – They can inhibit the formation of harmful proteins in Alzheimer's and thus offer protection against neurological disorders.

  • Anti-cancer potential – In laboratory studies, cannflavins have shown the ability to inhibit cancer cells and even induce programmed cell death.

  • Antiviral & Antiparasitic – Early indications show they may be active against viruses such as HIV and Zika virus.

  • Skin rejuvenation – By inhibiting glycation processes, they may contribute to smoother, younger-looking skin.


The entourage effect: working together for more power

Perhaps most fascinating is how cannflavins interact with other compounds in the cannabis plant. When combined with terpenes, cannabinoids, and their acid forms, a synergistic effect is created: the entourage effect . This effect demonstrates that the plant as a whole is often more potent than the sum of its individual compounds.

For example, terpenes not only enhance the aroma and flavor of cannabis but also enhance the absorption of cannaflavins in our bodies. And the acid forms of cannabinoids, such as CBDA, in turn, add additional anti-inflammatory and protective properties.


The vision of Peter Vermeul and CBD Spain

At CBD Spain , founded by researcher and pioneer Peter Vermeul , everything revolves around harnessing this full potential. Back in 2016, he developed a unique extraction method that preserves not only CBD but also the delicate terpenes, flavonoids, and acid forms.

This means a complete plant extract that contains as much of the cannabis plant's natural power as possible. An approach that perfectly aligns with the latest insights into the entourage effect and the role of cannflavins.


Why this is important for the future

The discovery and study of cannflavins opens the door to new, natural therapies. Their anti-inflammatory, neuroprotective, and anticancer properties make them valuable candidates for the medicine of tomorrow. Yet, research is still in full swing—and therein lies their strength: we are only just beginning to understand what cannflavins can do for our health.

👉 Want to explore the full depth, including chemical backgrounds, biological properties, and the latest research findings? Read the full article by Peter Vermeul.

Cannflavins - An In-Depth Exploration of the Cannabis Plant: Chemistry, Biological Activities, and Their Potential in Medicine - pdf NL

Cannflavins - An in-depth Exploration of the Cannabis plant Chemistry, Biological Activities and their Potential for Medicine - pdf EN

on our science page .