CBDa and Dentistry: The New Natural Breakthrough
CBDa and Dentistry: The New Natural Breakthrough
Healthy gums and strong jawbone form the foundation of strong teeth. But with the increasing prevalence of gum disease (such as periodontitis), researchers worldwide are searching for additional, natural ways to support healing processes. Interestingly, one plant compound is increasingly emerging: CBDa , the raw, non-decarboxylated form of CBD.
And leading the way in this research in Europe is Peter Vermeul , founder and owner of CBD Spain – the producer of the full-spectrum CBDa extracts we use at CBD & Herb . His latest research reveals fascinating insights that could completely change the way we view oral health.
In this blog post, we'll share our key findings without giving away all the depth. Because believe us, this topic deserves more in-depth exploration.
Why oral health is more than just brushing your teeth
Periodontitis—a serious form of gum disease—is one of the most common causes of bone loss in the jaw. This bone loss is often irreversible and can cause teeth to become loose or even fall out.
Traditional treatments mainly focus on:
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the removal of plaque and tartar
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inhibiting bacterial growth
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limiting inflammation
But real recovery of damaged jaw bone is complex and often limited.
Until now.
More and more studies show that cannabinoids, such as CBD and especially CBDa , can support the body in several ways with inflammation, bone growth and tissue repair.
The role of the endocannabinoid system in the mouth
We've known for some time that cannabis has a unique effect on the body. But only recently has it been discovered that the endocannabinoid system (ECS) also plays a significant role in the mouth—in gums, jawbone, and the periodontal ligament.
When inflammation occurs, CB1 and CB2 receptors increase in these tissues. This appears to be the body's way of trying to protect itself from further damage.
Why is this relevant?
CBDa and other cannabinoids can intervene precisely in these processes. Research shows that:
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they reduce pro-inflammatory substances such as TNF-α, IL-1β and PGE2
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they calm the immune system
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they counteract oxidative stress
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they can even inhibit bacterial growth
This makes cannabinoids not just interesting… but potentially revolutionary.
CBDa: More Than Just the 'Raw' Form of CBD
What makes CBDa so special is that it has its own unique action profile.
Unlike CBD:
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CBDa significantly inhibits COX-2 , an inflammatory enzyme that plays a central role in gum inflammation, pain and bone loss
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CBDa has a high bioavailability : it is better absorbed into the bloodstream
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activates additional receptors (such as 5-HT1A) that influence pain, stress and inflammation sensitivity
That's why CBDa has become increasingly important in high-quality full-spectrum extracts in recent years. At CBD Spain, CBDa is preserved in the extract using cold extraction techniques – a method Peter Vermeul has been refining for years.
From laboratory to real results: teeth that become firmer again
Perhaps the most impressive part of the research and real-world experience: users of CBDa-rich full-spectrum extracts report that loose teeth become more firmly repositioned in the jaw over time .
In several cases this was confirmed by dentists:
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X-rays showed recovery of jaw bone
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the periodontal tissue became healthier
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bone loss appeared to stabilize or even improve
Although not yet considered an official medical treatment, it is surprisingly well suited for:
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inhibiting bone breakdown (less RANKL, more OPG)
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stimulating bone growth
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reducing inflammatory damage
The fact that these processes appear to be visible not only in animal studies, but also in humans, makes the subject all the more relevant.
Antibacterial action: stronger than traditional mouthwashes?
Another intriguing part of the research:
various cannabinoids (CBD, CBG, CBC, CBDa) have been shown to be very effective against bacteria that cause plaque and gum inflammation.
In laboratory studies, cannabinoid-rich solutions killed more bacteria than two well-known toothpastes .
A mouthwash containing <1% CBD was even found to be more powerful than chlorhexidine , the gold standard in dentistry.
This opens the door to completely new oral care products – based on plant cannabinoids instead of synthetic antibacterial agents.
What does this mean for the future of oral care?
We are only just beginning.
CBDa is not (yet) an official medical drug in dentistry, but the initial research results are so promising that more and more universities, biological laboratories and dental research centers are starting to work with it.
There are even clinical studies underway on:
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CBD in toothpaste
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cannabinoid mouthwashes
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bone regeneration using cannabinoids
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anti-inflammatory in periodontitis
It is expected that these developments will take off in the coming years.
Why we at CBD & Herb are so excited about it
Our partnership with CBD Spain means that we have been working with extracts in which CBDa – not CBD – is central for years.
Not only because it appears to be a more powerful natural anti-inflammatory, but also because:
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it has a broader effect
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it is better absorbed
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it is consistently experienced by users as more soothing and effective
And thanks to Peter Vermeul's research, we are gaining unique insights into how these extracts work, not only in the body, but specifically in the mouth.
👉 Read the full scientific article by Peter Vermeul here.
Get inspired by the science behind natural oral care and discover how CBDa can play a role in the dental health of the future.